Progression of Protruding Plaque in Acute Coronary Syndrome Diagnosed by Serial Optical Coherence Tomography.

ABSTRACT: Background: Plaque protrusion after stent implantation is frequently observed in acute coronary syndrome (ACS) patients, yet studies on its long-term progression and clinical significance are limited. Methods: Seventy-eight ACS patients underwent optical coherence tomography (OCT)-guided PCI and follow-up OCT at 1 year. A total of 101 protruding lesions were classified into atherogenic neointima (AN) and non-AN groups based on OCT findings. Qualitative and quantitative assessments of protruding plaque, including irregularity and plaque intensity, were conducted. Results: AN developed in 17% of irregular protrusion (IP) lesions, whereas no smooth protrusion progressed to AN. Lesions in the AN group showed greater increases in protruding plaque volume (2.80 ± 0.46 mm

SUBMITTER: Aoki Y 

PROVIDER: S-EPMC12608650 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature