Genome-Wide Identification and Expression Analysis of Mitochondrial Dicarboxylate Carriers (DICs) in Medicago Under Aluminum Stress.

ABSTRACT: Aluminum (Al) is solubilized as phytotoxic Al³⁺ in acidic soils, rapidly inhibiting root elongation. To detoxify Al, plant roots secrete organic acids that chelate the ion. The transcription factor SENSITIVE-TO-PROTON-RHIZOTOXICITY1 (STOP1) regulates the export, distribution and metabolism of organic acids, which is crucial for Al resistance. Plant DICARBOXYLATE-CARRIERs (DICs) located in the inner mitochondrial membrane are presumed to exchange the dicarboxylates. However, whether Al or STOP1 modulates DIC expression to coordinate the organic acid shuttle remains unclear. Here, in the model legume Medicago truncatula, we identified three DIC genes and twelve in tetraploid Medicago sativa. Phylogenetic analysis places all Medicago DICs in a clade with

SUBMITTER: Yan C 

PROVIDER: S-EPMC12608790 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature