Preputial and scrotal cutaneous mast cell tumors in dogs show no evidence of inherently higher biologic malignancy.

ABSTRACT: Canine genital mast cell tumors (MCTs) have been associated with a poorer prognosis; however, no larger study has focused exclusively on MCTs in this region. This study aimed to retrospectively describe the clinicopathologic aspects and outcomes of dogs with cutaneous preputial and scrotal MCTs and compare the findings to historical data from cutaneous MCTs from other locations. Medical records from 2002 to 2024 from a single institution were reviewed and 91 dogs (35 preputial, 56 scrotal) treated surgically with or without adjuvant therapy and a minimum follow-up of 6 months were included. Tumors were graded according to Patnaik (preputial: 63% grade I, 31% grade II, 6% grade III; scrotal: 41% grade I, 38% grade II, 21% grade III) and Kiupel (preputial: 91% low-grade, 9% high-grade; scrot

SUBMITTER: Zagar Z 

PROVIDER: S-EPMC12609186 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature