Promising, but Not Completely Conclusive-The Effect of l-Theanine on Cognitive Performance Based on the Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Clinical Trials.

ABSTRACT: Background: Green tea (Camellia sinensis) has been consumed for centuries, and its beneficial effects on human health have been studied in recent decades. l-theanine, an active ingredient in green tea, has been used to improve cognition and mood. Although the effects of l-theanine on cognition have been investigated in clinical trials that have reported various results, these studies have not yet been critically evaluated in meta-analyses. Objectives: Our objective was to systematically evaluate the efficacy of l-theanine on cognitive functions compared to a placebo, in a meta-analysis based on randomized controlled trials (RCTs). Methods: PubMed, the Cochrane Central Register of Controlled Trials, Embase and Web of Science were searched for relevant studies unt

SUBMITTER: Matyus RO 

PROVIDER: S-EPMC12609247 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature