Early Palliative Care in Advanced Hematologic Malignancies: A Systematic Review of Patient-Centered Outcomes.

ABSTRACT: Background: Patients with hematologic malignancy (HM) experience high symptom burden (SB) and diminished quality of life (QOL). While early palliative care (EPC) benefits solid tumors, its impact in HM remains uncertain. Objectives: To systematically review the effects of EPC on patient-centered outcomes in individuals with HM. Methods: MEDLINE, Web of Science, Cochrane Library, and Scopus were searched for English-language articles published between 2020 and 2024. Eligible studies included adults with advanced HM receiving EPC compared with usual care, reporting outcomes on SB, QOL, place of death (POD), healthcare costs (HCCs), or healthcare utilization (HCU). All original study designs were considered. Critical appraisal was performed, and results were synthesized n

SUBMITTER: Fernandes-Almeida P 

PROVIDER: S-EPMC12609357 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature