Electrocrystallization of Calcium Oxalate Mediated by Electrospun Polymer Fiber Using Poly(acrylic acid-<i>co</i>-4-styrene sulfonate).

ABSTRACT: Calcium oxalate (CaOx) crystals play a central role in urolithiasis, a pathological crystallization process that remains difficult to prevent. In this study, electrospun polymeric fiber (EPF) meshes of poly(acrylic acid-co-styrene sulfonate) P(AA-co-SS) were fabricated by electrospinning (ES) under controlled positive (+) or negative (-) voltages. The influence of PAA and PSS homopolymers, as well as P(AA-co-SS) copolymers with varying compositions, was evaluated as anionic scaffolds in in vitro CaOx electrocrystallization (EC) experiments. The structural and morphological features of the EPF meshes were characterized by scanning electron microscopy with energy-dispersive spectroscopy (SEM-EDS), Fourier-transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD

SUBMITTER: Neira-Carrillo A 

PROVIDER: S-EPMC12610098 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature