Variations in Flavonoid Metabolites Among <i>Forsythia suspensa</i> Populations in Response to Environmental Heterogeneity.

ABSTRACT: Forsythia suspensa (Thunb.) Vahl, a pharmacopoeial medicinal plant, is valued for its therapeutic efficacy in heat-clearing detoxification, dispelling wind-heat, and promoting blood circulation to resolve stasis. Flavonoids, ubiquitous secondary metabolites in F. suspensa, are critically linked to pharmacological activities and exhibit diverse biological functions. To elucidate the chemotypic divergence and ecological drivers of its bioactive compounds, we conducted flavonoid metabolomic profiling across ten wild populations F. suspensa using UPLC-MS/MS. Results revealed significant inter-population variation in all twenty-nine flavonoid metabolites analyzed. Notably, Notably, Cinchonain Ic was significantly enriched in the JX population, Flavanomarein in the LT popula

SUBMITTER: Zhou S 

PROVIDER: S-EPMC12610222 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature