Biointegrated Conductive Hydrogel for Real-Time Motion Sensing in Exoskeleton-Assisted Lower-Limb Rehabilitation.

ABSTRACT: Chronic lower-extremity wounds in patients undergoing exoskeleton-assisted rehabilitation require materials that can both protect tissue and enable real-time physiological monitoring. Conventional dressings lack dynamic sensing capability, while current conductive hydrogels often compromise either adhesion or electronic performance. Here, we present a biointegrated hydrogel (CPSD) composed of carboxymethyl chitosan (CMCS) and poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) forming the conductive backbone, integrated with dopamine-functionalized sodium alginate (SD); the network is assembled via electrostatic complexation and carbodiimide (EDC/NHS)-mediated covalent crosslinking. The resulting hydrogel exhibits a dense, tissue-conformal porous network with tunable swelli

SUBMITTER: Li M 

PROVIDER: S-EPMC12610655 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature