Monocyte count predicts low-level viremia in people living with HIV receiving antiretroviral therapy: A retrospective cohort study.

ABSTRACT: Low-level viremia (LLV) remains a clinical challenge in people living with HIV (PLWH) receiving antiretroviral therapy (ART), with its pathogenesis and predictors not fully understood. Recent evidence suggests a role for monocytes in HIV persistence and immune activation. However, the clinical significance of monocyte count (MONO) as a predictive biomarker for LLV has not been fully elucidated. This study aimed to evaluate whether baseline (MONO) is associated with the risk of developing LLV in PLWH. We conducted a retrospective cohort study involving 671 PLWH on ART at Ningbo Yinzhou No. 2 Hospital. Participants were categorized into tertiles based on baseline MONO. The primary outcome was the incidence of LLV. Cox proportional hazards regression analyses were performed to assess the asso

SUBMITTER: Xia T 

PROVIDER: S-EPMC12611236 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature