Cost-Effectiveness of CT Colonography Under Real-World Colorectal Cancer Screening Adherence for Black and White Populations.

ABSTRACT:

Background

Given the Centers for Medicare and Medicaid Services' coverage of screening CT colonography (CTC) beginning in January 2025, we evaluated the cost-effectiveness of CTC for colorectal cancer (CRC) screening by race (Black and White) and gender, considering real-world screening adherence.

Methods

A microsimulation model compared CRC screening strategies in average-risk adults by race and gender, incorporating 2010-2019 U.S. data on disease progression and real-world screening adherence for colonoscopy and fecal immunochemical test (FIT). Five strategies were compared: (1) status quo (choice between colonoscopy and FIT); (2) CTC every 5 years; (3) colonoscopy every 10 years; (4) annual FIT; and (5) multitarget stool DNA test every 3 years, plus no screening. Lifetime

SUBMITTER: Kao SZ 

PROVIDER: S-EPMC12612557 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature