Pentadecanoic Acid Supplementation in Young Adults with Overweight and Obesity: A Randomized Controlled Trial.

ABSTRACT:

Background

Obesity and its associated comorbidities are major public health concerns for which nutrition is central to disease prevention and management. Pentadecanoic acid (C15:0) has the potential for beneficial effects on obesity, but supplementation has not been studied in humans.

Objectives

The primary objective was to investigate changes in plasma C15:0 levels after daily supplementation for 12 wk. Additionally, the study aimed to assess safety and tolerability as well as measure potential markers of physiologic response.

Methods

This was a single-center, double-blind, randomized, controlled, 2-arm trial of 200 mg C15:0 or placebo daily for 12 wk in young adults with overweight or obesity.

Results

A total of 30 participants with a mean age of 20.0 ± 2.1 y

SUBMITTER: Robinson MK 

PROVIDER: S-EPMC12612588 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature