Pericoronary Adipose Tissue as a Predictor of Diastolic Dysfunction: A New Paradigm in Coronary Artery Disease Assessment.

ABSTRACT:

Background and objectives

Pericoronary adipose tissue (PCAT) is linked to coronary artery disease (CAD) progression through compositional changes that disrupt adipose homeostasis and affect vascular biology. This study explores how PCAT characteristics - volume and fat attenuation index (FAI)-relate to CAD severity and left ventricular (LV) function.

Methods

This study included 100 patients with suspected CAD who underwent coronary computed tomography angiography (CCTA) and echocardiography between September 2023 and July 2024. PCAT volume, FAI and thickness were measured along coronary arteries (right coronary artery [RCA], left anterior descending [LAD], and left circumflex [LCX]). CAD severity was assessed using the Gensini score, while LV structural and functional metric

SUBMITTER: Agarwal R 

PROVIDER: S-EPMC12612604 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature