Placental Vascular Resistance and Offspring Growth From Birth to Age 2 Years.

ABSTRACT:

Importance

Umbilical artery Doppler indices provide indirect measures of placental function, with elevated vascular resistance associated with adverse perinatal outcomes, but their association with postnatal growth remains understudied.

Objective

To examine the association between placental vascular resistance and early-childhood physical growth.

Design, setting, and participants

This cohort study used hospital electronic medical records and Maternal and Child Health Information System data of all singleton live births from May 18, 2012, to October 30, 2023, at Wuhan Children's Hospital (Wuhan Maternal and Child Health Hospital).

Exposure

Placental vascular resistance was assessed through routine prenatal Doppler ultrasonography measurements of pulsatility inde

SUBMITTER: Xu L 

PROVIDER: S-EPMC12612932 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature