C-reactive protein-albumin-lymphocyte index and atrial fibrillation recurrence after radiofrequency ablation in heart failure.

ABSTRACT: Atrial fibrillation (AF) frequently coexists with heart failure (HF), and predicting post-ablation recurrence remains challenging. This study evaluated the association between the C-reactive protein-albumin-lymphocyte (CALLY) index and post-ablation AF recurrence. We enrolled 159 patients who underwent first-time ablation. Over 12 months, 28.9% experienced recurrence. Associations were tested using Cox regression, Kaplan-Meier curves, restricted cubic splines (RCSs), receiver operating characteristic analysis, and subgroup analyses, with confirmation in an external cohort. Forty-six patients (28.9%) recurred. After multivariable adjustment, the highest CALLY index quartile had lower recurrence risk than the lowest (hazard ratio [HR] = 0.203; 95% confidence interval [CI]: 0.067-0.615; p<

SUBMITTER: Jiang X 

PROVIDER: S-EPMC12613050 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature