Effects of aerobic exercise on late effects and quality of life in long-term breast cancer survivors: a randomized controlled trial.

ABSTRACT:

Background

Breast cancer survivors (BCSs) are at increased risk of late effects. While research has reported positive effects of exercise therapy on fatigue and health-related quality of life (HRQoL) among short-term BCSs, evidence in long-term survivors remains scarce.

Methods

The CAUSE (CArdiovascUlar Survivors Exercise) trial was a 2-armed randomized controlled trial. Long-term BCSs were assigned to 5 months of thrice-weekly supervised aerobic exercise or usual care. Late effects and HRQoL were assessed by Chalder Fatigue Questionnaire, European Organization for Research and Treatment of Cancer QLQ-BR23 and QLQ-C30 questionnaires, and Scale for Chemotherapy-Induced Long-term Neurotoxicity at baseline (T0), post-intervention (T1), and 1-year follow-up (T2).

Results

SUBMITTER: Johansen SH 

PROVIDER: S-EPMC12613246 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature