TCGA molecular subtypes in endometriosis-associated ovarian cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

Endometriosis-associated ovarian cancer (EAOC) mainly includes endometrioid ovarian cancer (ENOC) and clear cell ovarian cancer (CCOC). The Cancer Genome Atlas (TCGA) revealed four molecular subtypes of endometrial cancer (EC) in 2013, which have been proven pivotal in the diagnostic, prognostic and therapeutic domains of EC. Existing evidence indicates that EC and EAOC molecular analysis have similar significance. This review aims to investigate the distribution, staging and prognostic characteristics of molecular subtypes in EAOC.

Methods

PubMed, Embase and Web of Science were systematically searched from January 2013 to December 2023 using predefined keywords. Patient characteristics, including stage and prognostic characteristics, were extracted from the selec

SUBMITTER: Ye L 

PROVIDER: S-EPMC12613302 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature