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Risk of drug-induced liver injury in chronic hepatitis C and tuberculosis co- infection: a systematic review and meta- analysis.


ABSTRACT:

Purpose

Antituberculosis drug-induced liver injury (ATLI) is a common and serious adverse drug reaction of tuberculosis treatment. The impact of ATLI in patients with chronic hepatitis C is unclear. The aim of this study is to evaluate the prevalence of DILI in patients with and without HCV and assess its impact in the prevalence of ATLI.

Methods

The preferred reporting items for systematic reviews and meta-analyses standards were followed, and the protocol was registered in PROSPERO. In this study, PubMed, Web of Sciences, EMBASE, the Cochrane Library were searched from inception to 21 May 2024. We performed a systematic review and meta-analysis of studies of the papers relevant to compare the prevalence of anti-tuberculosis drug-induced liver injury in patients with and wi

SUBMITTER: Wei X 

PROVIDER: S-EPMC12613362 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature