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Soluble urokinase plasminogen activator receptor and perioperative complications: a systematic review.


ABSTRACT:

Background

Better informative predictive tools are required to improve risk-stratification in patients undergoing surgery. Soluble urokinase-type plasminogen activator receptor (suPAR) has the potential to predict postoperative complications. The primary objective of this systematic review was to evaluate the association between suPAR measured around the time of surgery and perioperative complications.

Methods

We systematically reviewed studies indexed in Embase or PubMed from inception up to October 8, 2024. We included studies evaluating the association between suPAR measured around surgery and perioperative complications captured up to 90 days after surgery. We excluded case reports, reviews, editorials, studies with non-human participants, and clinical practice guideline

SUBMITTER: Gungor AB 

PROVIDER: S-EPMC12613401 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature