Impact of COVID-19 on pituitary function: a cross-sectional study in southern Iran.

ABSTRACT:

Objectives

COVID-19 is associated with multiorgan dysfunction, including the endocrine system, and severe illness often involves endocrine-metabolic issues. We investigated hormonal axes in hospitalized COVID-19 patients in Iran and their correlation with disease severity, outcomes, and inflammatory biomarkers.

Methods

We conducted a cross-sectional study with 200 hospitalized COVID-19 patients. An initial endocrinology panel assessed thyroid hormones, gonadal hormones, adrenal hormones, and prolactin levels. Disease severity was evaluated using the COVID-19 Severity Index.

Results

Of 183 patients analyzed, most had severe (21.7%) or critical (63.3%) infections. Abnormal hormone levels were common, with 26.8% having non-thyroidal illness syndrome (NTIS), 30.1% suspect

SUBMITTER: Sheikhi S 

PROVIDER: S-EPMC12613459 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature