Pain assessment and treatment in patients with mucopolysaccharidoses: a French multicentric pediatric study.

ABSTRACT:

Background

Mucopolysaccharidoses (MPS) are a group of rare genetic lysosomal storage disorders with a wide spectrum of clinical severities. Chronic pain is frequent but difficult to assess. The aim of this study was to evaluate the detection and management of pain in pediatric MPS patients.

Methods

Pain-related data were retrospectively collected from the medical records of pediatric MPS patients from five French centers for inborn metabolic disorders. A national online survey was also conducted about the feelings of patients and/or their families and of healthcare professionals about the detection and management of pain in pediatric MPS patients.

Results

The medical records of 48 patients with all subtypes of MPS were analyzed. Pain was frequent and recurrent in MPS

SUBMITTER: Blin M 

PROVIDER: S-EPMC12613516 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature