Gamma-glutamyltransferase and the survival of hepatocellular carcinoma patients after transarterial chemoembolization: a meta‑analysis and systematic review.

ABSTRACT:

Objective

Plentiful studies have reported that preoperative gamma-glutamyltransferase (GGT) had a strong relationship with the prognosis of hepatocellular carcinoma (HCC) patients treated with transarterial chemoembolization (TACE). Nevertheless, due to the small sample size and contradictory conclusions, the predictive function remains indefinite. To investigate the relationship between pretreatment GGT value and clinical outcomes in HCC patients undergoing TACE, a meta-analysis including 10 articles was constructed.

Method

Studies were searched in PubMed, Embase, Web of Science, Cochrane Library, CNKI, and Wanfang database. Pooled Hazard Ratio (HR) or Odd Ratio (OR) with its 95% confidence intervals was calculated to evaluate the prognostic value of pretreatment GGT in HCC

SUBMITTER: Huang Z 

PROVIDER: S-EPMC12613662 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature