Anticoagulation therapy for intra-abdominal hypertension in patients with acute pancreatitis.

ABSTRACT:

Background

Intra-abdominal hypertension (IAH) is a common complication in patients with acute pancreatitis (AP) and can lead to multiple organ failure. The efficacy of anticoagulant therapy for IAH in patients with acute pancreatitis is unclear. The objective of this study aimed to investigate the effects of anticoagulant therapy on IAH in patients with acute pancreatitis.

Materials and methods

A total of 49 AP patients with IAH were included in this retrospective study, with 34 patients in the anticoagulant group and 15 patients in the non-anticoagulant group. The effects of anticoagulant therapy on intra-abdominal pressure, inflammation markers, disease severity, and imaging indices were compared between the two groups.

Results

The anticoagulant group had significan

SUBMITTER: Ge Y 

PROVIDER: S-EPMC12613669 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature