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Association of the uric acid-to-high-density lipoprotein cholesterol ratio with vitamin D deficiency in postmenopausal women: evidence from NHANES 2005-2016.


ABSTRACT:

Background

The relationship between vitamin D deficiency and the uric acid-to-high-density lipoprotein cholesterol ratio (UHR) in postmenopausal women remains unclear. This study aims to investigate the association between these variables and to evaluate the potential interaction between UHR and waist circumference (WC).

Methods

Data from 5,155 postmenopausal women who participated in the National Health and Nutrition Examination Survey (NHANES) between 2005 and 2016 were included in this cross-sectional investigation. Weighted regression analysis served as the primary methodology employed to examine the association between UHR and vitamin D deficiency. Furthermore, interaction analysis, sensitivity analysis, and restricted cubic splines (RCS) were also conducted.

Results

SUBMITTER: Huang X 

PROVIDER: S-EPMC12613852 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature