Pericoronary fat attenuation index on coronary CT angiography and cardiovascular risk in patients with coronary artery disease and chronic kidney disease.

ABSTRACT:

Background

The pericoronary fat attenuation index (pFAI), derived from coronary computed tomography angiography (CCTA), is an emerging marker of local inflammation of coronary arteries. Its prognostic significance in patients with coronary artery disease (CAD) and chronic kidney disease (CKD), which share common inflammatory pathways, remains uncertain. This study aimed to assess the associations between the pFAI and cardiovascular and mortality risk in patients with concurrent CAD and CKD.

Methods

Patients with both CAD and CKD who underwent CCTA within 1 year of invasive coronary angiography were included from Cardiorenal Improvement-Ⅱ. The pFAI was measured around the proximal 40 mm of the left anterior descending artery (LAD), left circumflex artery (LCX), and right coro

SUBMITTER: Lu X 

PROVIDER: S-EPMC12613875 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature