IPI score as a new prognostic index in extensive stage small cell lung cancer.

ABSTRACT:

Background

Personalized prognostic assessment in extensive-stage small cell lung cancer (ES-SCLC) necessitates a comprehensive understanding of systemic inflammatory markers and their impact on survival outcomes. This study aimed to evaluate the prognostic significance of a novel Inflammatory Prognostic Index (IPI) score, derived from four inflammation-related biochemical markers-albumin, C-reactive protein (CRP), neutrophils, and lymphocytes-in patients with ES-SCLC.

Methods

Patients diagnosed with ES-SCLC were eligible if adequate clinical, pathological, and follow-up data were available. The IPI score was derived using the formula: C-reactive protein × neutrophil-to-lymphocyte ratio (NLR)/serum albumin. The threshold value for the IPI score was identified using receiver o

SUBMITTER: Agaoglu AB 

PROVIDER: S-EPMC12614095 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature