Randomized Trial of Targeted Indoor Spraying to Prevent Aedes-Borne Diseases.

ABSTRACT:

Background

Targeted indoor residual spraying focuses insecticide applications on common resting surfaces of Aedes aegypti mosquitoes (an arboviral disease vector) in houses, such as exposed lower sections of walls and under furniture.

Methods

We conducted a two-group, parallel, unblinded, cluster-randomized trial in Merida, Mexico, to quantify the efficacy of targeted indoor residual spraying for preventing aedes-borne diseases (chikungunya, dengue, or Zika). Children 2 to 15 years of age were enrolled from households in 50 clusters of five-by-five city blocks. Households in 25 clusters received an annual application of targeted indoor residual spraying (intervention) before each season of aedes-borne disease (July through December). All clusters received routine Mini

SUBMITTER: Dean NE 

PROVIDER: S-EPMC12614283 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature