Impact of the New Definition on the Prognosis of Patients With Pulmonary Hypertension Compared to the Classic Definition.

ABSTRACT:

Background and objectives

The 2022 European Society of Cardiology (ESC)/European Respiratory Society (ERS) guidelines updated the definition of pulmonary hypertension (PH). This study aimed to evaluate implications of the new PH definition.

Methods

A retrospective analysis of a single-center right heart catheterization registry (April 2016-July 2023) was conducted. Patients were classified using the classic definition (mean pulmonary arterial pressure [mPAP] ≥25 mmHg, pulmonary vascular resistance [PVR] >3 Wood units [WU]) and the new definition (mPAP >20 mmHg, PVR >2 WU). The primary outcome was a composite of cardiovascular death or heart failure (HF) hospitalization over a maximum follow-up of 5 years.

Results

Among 314 patients (median age, 62.5 years; male, 50.3%

SUBMITTER: Lee SY 

PROVIDER: S-EPMC12614430 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature