Contemporary Burden of Cardiovascular Disease in Pregnancy: Insights From a Real-World Pregnancy Electronic Health Record Cohort.

ABSTRACT:

Background

Cardiac and vascular complications are the leading causes of maternal mortality and morbidity, but the contemporary burden of and secular trends in pregnancy-related cardiovascular complications are not well-characterized. We developed a multi-institutional electronic health record-based pregnancy cohort with rigorously defined cardiovascular outcomes to examine trends in prevalence of maternal cardiovascular comorbidities and cardiovascular disease (CVD) and incidence of pregnancy-related cardiovascular complications.

Methods

We identified pregnancy encounters that occurred between 2001 and 2019 from a primary care electronic health record cohort using International Classification of Diseases and Current Procedural Terminology codes. We used regular expressions t

SUBMITTER: Lau ES 

PROVIDER: S-EPMC12614638 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature