Alkaline Phosphatase to Albumin Ratio as a Novel Predictor of All-Cause Mortality in Critically Ill Patients With Atrial Fibrillation.

ABSTRACT:

Background

Alkaline phosphatase to albumin ratio (APAR) is an emerging prognostic indicator for sepsis, cancer, and coronary artery disease. However, the predictive value of APAR in patients with atrial fibrillation (AF) has not been investigated yet. Therefore, this study aims to explore the association between APAR and the risk of mortality in critically ill patients with AF.

Methods

The data of AF patients were extracted from the Medical Information Mart for Intensive Care-IV (MIMIC-IV) database. Patients with AF were divided into three groups according to the APAR tertiles. Study outcomes were defined as 28-day and 365-day all-cause mortality. The Kaplan-Meier analysis was conducted to compare the survival rates between groups. Cox proportional hazards regression and res

SUBMITTER: Wu H 

PROVIDER: S-EPMC12614730 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature