Cortical state contributions to neuronal response variability in the early visual cortex: A system identification approach.

ABSTRACT: Neurons in the early visual cortex respond selectively to multiple features of visual stimuli, but they respond inconsistently to repeated presentation of the same visual stimulus. Such trial-to-trial response variabilities are often treated as random noise and addressed by simple trial-averaging to obtain the stimulus-driven response. However, response variability may primarily be caused by non-sensory factors, particularly by variations in cortical state. Here we recorded and analyzed neuronal spiking activity in response to natural images from areas 17 and 18 of cats, along with local population neuronal signals, i.e., local field potentials (LFPs) and multi-unit activity (MUA). Single neurons showed highly varying degrees of trial-to-trial response variability, even when recorded simul

SUBMITTER: Sooriyaarachchi J 

PROVIDER: S-EPMC12614811 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature