Oxidative balance score and all-cause mortality among hypertensive individuals.

ABSTRACT:

Background

Oxidative stress contributes to hypertension and its complications. The oxidative balance score (OBS) could therefore provide insight into the relationship with mortality in hypertensive individuals. We aimed to investigate the association between OBS and all-cause mortality using data from National Health and Nutrition Examination Survey 2007-18.

Methods

Our sample comprised 11 196 hypertensive participants. We calculated OBS based on dietary and lifestyle factors and categorised participants accordingly into quartiles. We used Cox proportional hazards model to assess associations between OBS and mortality, and restricted cubic spline (RCS) analyses to determine dose-response relationships. Lastly, we conducted Kaplan-Meier survival curves and stratified/sensitiv

SUBMITTER: Huang LZ 

PROVIDER: S-EPMC12615001 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature