Meta-Research Study on the Quality of Randomized Controlled Trials Evaluating Drug Therapy for Impetigo.

ABSTRACT:

Introduction

Impetigo is a common, highly contagious bacterial skin infection primarily affecting children. Treatment usually involves topical or oral antibiotics, and numerous clinical trials have been published to support these therapeutic approaches.

Objectives

To evaluate the methodological quality of randomized clinical trials (RCTs) on the pharmacological treatment of impetigo in children and adolescents.

Methods

This meta-research evaluated RCTs on systemic or topical pharmacological treatments for impetigo in children and adolescents. A comprehensive literature search was conducted in September 2024 across MEDLINE, Embase, CENTRAL, and LILACS databases. The methodological quality of the included RCTs was assessed using the Cochrane Risk of Bias tool. Data are

SUBMITTER: Rodrigues JC 

PROVIDER: S-EPMC12615057 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature