Assessing the accuracy of automated CT perfusion software in excluding acute stroke: a comparative study of two software packages.

ABSTRACT:

Background

Computed tomography perfusion (CTP) is frequently used for the rapid assessment of suspected acute ischemic stroke (AIS). However, small lacunar infarcts often remain undetected by automated software, leading to false negatives and additional imaging. We compared the specificity of two commonly used CTP software packages in patients without evidence of stroke on follow-up diffusion-weighted imaging (DWI).

Methods

In this single-center retrospective study, 58 consecutive patients with suspected AIS but negative follow-up DWI-MRI were included. All patients underwent CTP on the same scanner. Perfusion data were processed using (1) syngo.via (Siemens Healthcare) with three parameter settings-A: CBV < 1.2 mL/100 mL, B: additional smoothing filter, and C: rCBF <30%-and

SUBMITTER: Thormann M 

PROVIDER: S-EPMC12615249 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature