Carbon Ion Versus Photon-based Stereotactic Ablative Radiation Therapy for Patients with Choroidal Melanoma.

ABSTRACT:

Purpose

To our knowledge, no study has compared the treatment outcomes of carbon ion radiation therapy (CIRT) and photon-based stereotactic ablative radiation therapy (SABR) in patients with choroidal melanoma. This study aimed to evaluate the treatment outcomes of patients with choroidal melanoma treated with CIRT or photon-based SABR.

Methods and materials

This study included 346 patients with localized choroidal melanoma who received CIRT or photon-based SABR between April 2001 and November 2021. Patients in the CIRT group received a median of 70 Gy delivered in a median dosage of 14 Gy per fraction, and patients in the SABR group received a median of 60 Gy delivered in a median dosage of 15 Gy per fraction. Propensity score matching (PSM) was performed to account for dif

SUBMITTER: Kim J 

PROVIDER: S-EPMC12615358 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature