Association between the ratio of triglyceride to high-density lipoprotein cholesterol (TG/HDL-c) and chronic kidney disease risk: a large-scale cross-sectional study in a Chinese population.

ABSTRACT:

Objective

The association between lipid metabolism markers, particularly the TG/HDL-c ratio, and kidney dysfunction has not been thoroughly investigated in Chinese wellness examination cohorts. This study examines the correlation between these parameters and evaluates the role of TG/HDL-c as an independent predictor of CKD.

Methods

Our multicenter investigation encompassed data from 33,850 consecutive participants across eight major Chinese metropolitan areas (Shanghai, Guangzhou, Wuhan, Dalian, Zhengzhou, Lanzhou, Luzhou, and Guangxi). To evaluate the relationship between TG/HDL-c ratio and CKD, we employed multiple statistical approaches. The primary analysis utilized binary logistic regression to assess the independent association between these variables. We further chara

SUBMITTER: Liao Y 

PROVIDER: S-EPMC12615472 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature