A splicing regulator, SR45, suppresses plant immunity by regulating salicylic acid pathway in <i>Arabidopsis thaliana</i>.

ABSTRACT: Facing constant challenges from various pathogens and pests, plants have evolved different strategies to defend themselves both locally and systemically. A global change in RNA metabolism is one of the necessary steps to mount a long-lasting immunity against present and future invasions. Arabidopsis serine/arginine-rich 45 (SR45) is an evolutionarily conserved RNA-binding protein that regulates multiple steps of RNA metabolism. Our prior study suggested that SR45 acts as a negative regulator of plant immunity. To better understand the molecular mechanism for SR45's defense role, we examined the metabolic profile in both Col-0 and sr45-1. The results showed a significant accumulation of pipecolic acid (Pip), salicylic acid (SA), and other potential defense compounds in sr45

SUBMITTER: Bui A 

PROVIDER: S-EPMC12615492 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature