Reward and punishment learning among people with a lifetime history of anxiety, depression, and substance use disorder.

ABSTRACT: Reward and punishment learning are critical across multiple clinical populations. The Iowa Gambling Task (IGT) is frequently used to assess these constructs and multiple forms of psychopathology are associated with IGT performance. However, it is not clear whether alterations in IGT performance are general to psychopathology or specific to different forms of psychopathology. Thus, we examined whether IGT performance was uniquely predicted by anxiety, depression, and substance use disorder. We tested a sample of adults (N = 293) on the play-or-pass version of the IGT. We characterized behavior using a hierarchical Bayesian computational model, formalizing parameters underlying task behavior. With the model, we examined unique associations between IGT performance and lifetime diagnostic hist

SUBMITTER: Haynes JM 

PROVIDER: S-EPMC12615540 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature