Nonlinear association between blood cadmium levels and periodontitis: a cross-sectional study from NHANES 2011-2014.

ABSTRACT:

Objectives

The relationship between blood cadmium levels and the risk of periodontitis remains unclear. This study aimed to explore the association between blood cadmium concentrations and periodontitis in a large sample of the U.S. population from 2011 to 2014.

Methods

This cross-sectional study analyzed data from 5215 participants in the National Health and Nutrition Examination Survey (NHANES) 2011-2014. Blood cadmium levels were the exposure variable, and periodontitis was the outcome variable. Multivariate logistic regression and a two-piecewise linear regression model were used to examine the nonlinear relationship between blood cadmium levels and periodontitis. Stratified analyses were conducted to identify subgroups at higher risk.

Results

The study identified

SUBMITTER: Gao C 

PROVIDER: S-EPMC12615595 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature