Dynamic biomarker trajectories in the first 72 h after infarct-related cardiac arrest: a novel approach to early risk stratification.

ABSTRACT:

Background

Cardiac arrest caused by acute myocardial infarction (AMI) is associated with high mortality. Although risk stratification scores exist, they rely primarily on static variables obtained at admission, which do not capture the dynamic pathophysiology of the post-resuscitation phase. This study aimed to evaluate the prognostic value of serial biomarker trajectories during the first 72 h after AMI-induced cardiac arrest.

Methods

In this single-center cohort study, 181 patients with AMI-induced cardiac arrest between 2018 and 2024 were analyzed. Routinely measured laboratory biomarkers were assessed over the first three days in the intensive care unit (ICU). Multivariable logistic regression models adjusted for key clinical covariates were used to evaluate associations

SUBMITTER: Mohsennia J 

PROVIDER: S-EPMC12615751 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature