Temporoparietal brain structures support sentence processing across the adult lifespan.

ABSTRACT: Although older adults maintain most language abilities, they can experience declines in complex sentence comprehension. How brain structure and function mediate age-related changes in sentence processing remains underspecified. Here, using a novel neuroimaging approach to perform region-based mediation statistics, we investigated the neural correlates of memory capacity and sentence processing in 187 neurologically intact adults aged 20-80 years. Working and auditory-verbal short-term memory were measured using two National Institutes of Health Cognitive Toolbox tasks, and reading sentence processing was measured with a self-paced reading (SPR) task consisting of closely matched noncanonical (object-relative; OR) and canonical (subject-relative; SR) conditions. Behaviorally, we found that

SUBMITTER: Riccardi N 

PROVIDER: S-EPMC12616153 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature