Interventional Treatment vs Conservative Management of Unruptured Brain Arteriovenous Malformations.

ABSTRACT:

Importance

The optimal management of unruptured brain arteriovenous malformations (AVMs) remains controversial, as the risk-benefit balance between interventional treatment and conservative management is unclear. While ARUBA (A Randomized Trial of Unruptured Brain AVMs) favored conservative management in the short term, methodologic limitations and limited follow-up have left uncertainty regarding long-term outcomes.

Objective

To evaluate the association between interventional treatment and hemorrhage-free survival, compared with conservative management, in patients with unruptured AVMs.

Design, setting, and participants

This cohort study used a target trial emulation approach based on data from the Multimodality Treatment for Brain Arteriovenous Malformation in Mainl

SUBMITTER: Han H 

PROVIDER: S-EPMC12616460 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature