Thermostable Bacterial Esterases From Lipase Family 1.5 Degrade Compostable Polyesters PBAT and PBSA.

ABSTRACT: The escalating plastics crisis, exacerbated by the accumulation of nonbiodegradable polyesters in the environment, has necessitated the exploration of sustainable waste management solutions such as enzymatic hydrolysis in industrial recycling. So far, the focus of these efforts has been on cutinase-related polyethylene terephthalate (PET) degrading carboxylesterases, or PETases. In this work, we report the discovery and initial activity screen of previously uncharacterized, thermostable enzymes with polyesterase activity through comprehensive phylogenetic and sequence analysis of a bacterial family of esterases, Lipase Family 1.5. These enzymes are related to the previously identified polybutylene succinate co-terephthalate (PBAT) degrading carboxylesterases Cl_EstA and Cl_EstB from Clostr

SUBMITTER: Ahmed FH 

PROVIDER: S-EPMC12616515 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature