Predictors of Bronchodilator Response on Oscillometry and Spirometry in School-Age Children With Bronchopulmonary Dysplasia.

ABSTRACT: This study aimed to identify predictors of bronchodilator response (BDR) on oscillometry and spirometry for school-age children with bronchopulmonary dysplasia (BPD). We hypothesized that clinical and neonatal characteristics influence BDR. Participants aged 6-12 years enrolled in the Air Quality, Environment and Respiratory Outcomes in BPD (AERO-BPD) observational study performed pre- and post-bronchodilator oscillometry and spirometry. Measures included forced expiratory volume in 1 s (FEV₁), forced vital capacity (FVC), FEV₁/FVC, airway resistance at 5 Hertz (Hz, R₅), resistance between 5 Hz and 19 Hz (R_5-19), resonant frequency (F_res), reactance at 5 Hz (X₅), and area under the curve between F_res and X_5</

SUBMITTER: Lee JX 

PROVIDER: S-EPMC12616620 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature