Exposure to ambient air pollution during pregnancy and risk of early-onset breast cancer.

ABSTRACT:

Background

Air pollution has been linked to breast cancer risk, but previous studies have seldom considered specific exposure windows, like pregnancy. During pregnancy the breast undergoes substantial changes and exposures may have a stronger impact than if they occurred during other time periods. This study aims to identify associations between ambient air pollution exposure during pregnancy and risk of early-onset breast cancer.

Methods

Using nationwide data from Swedish registers, we constructed a cohort consisting of all cancer-free women in Sweden giving birth to their first child between 1991 and 2015. Residential exposure to nitrogen dioxide (NO₂), particulate matter < 10 μm (PM₁₀) and < 2.5 μm (PM_2.5) were modelled based on air pollut

SUBMITTER: Edlund J 

PROVIDER: S-EPMC12616941 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature