Effect of acupuncture on neuroinflammatory responses in depression animals: a systematic review and meta-analysis.

ABSTRACT:

Background

Depression causes many negative effects and even death to patients; the burden on society is also heavy in terms of economics. The neuroinflammatory mechanism of acupuncture regulating depression is unclear. Thus, this study evaluated the effect of acupuncture on neuroinflammatory responses in depression animals and provided a clinical reference for depression treatment.

Methods

The Web of Science, Embase, the Cochrane Library, PubMed, CNKI, WanFang, CBM, and VIP databases were searched. The SYRCLE Risk of Bias Tool was used to assess bias in the studies. Meta-analysis was performed using Stata 15.0. The sources of heterogeneity were explored using subgroup analysis, and stability was evaluated using sensitivity analysis. Quality of evidence for outcomes was asses

SUBMITTER: Ni D 

PROVIDER: S-EPMC12617222 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature