Associations Between Malignant Tumors and Alzheimer's Disease: A Cross-Sectional Study.

ABSTRACT:

Introduction

Although there is potential overlap in the pathological and physiological mechanisms underlying malignant tumors and Alzheimer's disease (AD), a significant gap remains in the epidemiological evidence supporting their association. We used data from the National Health and Nutrition Examination Survey (NHANES) to elucidate the epidemiological relationship between malignant tumors and AD.

Methods

We analyzed data from NHANES from 2013 to March 2020, prior to the COVID-19 pandemic, including 9274 participants aged ≥ 20 years. Multivariate logistic regression was used to explore the link among malignant tumors, tumor types, and AD risk. Sensitivity analyses were performed to evaluate the robustness of the association with neurofilament light chain levels, composite

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC12617259 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature