Association between obesity indices, insulin resistance markers, and osteoarthritis in middle-aged and elderly Chinese adults.

ABSTRACT:

Background

Previous studies have indicated an association between osteoarthritis (OA), obesity, and insulin resistance (IR). However, current literature lacks sufficient clinical data to fully elucidate the relationship between obesity indices, insulin resistance surrogates (IR surrogates), and OA in China's middle-aged and elderly population. This study aims to investigate the correlation between obesity indices [body fat percentage (BFP), lipid accumulation product (LAP), body mass index (BMI), waist-to-height ratio (WHtR)], IR surrogates [triglyceride-glucose (TyG) index and its derivatives: TyG with waist circumference (TyG-WC), TyG-BMI, TyG-WHtR, and OA risk, and evaluate the diagnostic efficacy of these indices for OA.

Methods

This study utilized data from the China He

SUBMITTER: Zhang S 

PROVIDER: S-EPMC12617301 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature