Adjuvant External Beam Radiotherapy in Differentiated Thyroid Cancers: An Audit of Clinical Practice, Adapting to New Evidence.

ABSTRACT:

Introduction

There is limited evidence on the role of adjuvant external beam radiotherapy in differentiated thyroid cancer (DTC).

Methods

We conducted a retrospective study of patients with DTC treated with adjuvant Intensity Modulated radiotherapy (IMRT) from 2011 to 2024.

Results

Fifty-nine patients were analyzed with median follow-up of 53 months. All the patients had undergone total thyroidectomy. Gross extrathyroidal extension was seen in 76% of patients, while 54% had R1/R2 resection. High-risk histological types were seen in 51% of patients, while 34% had recurrent disease. The 5-year locoregional control (LRC) was 89.3% while 5-year overall survival (OS) was 84.6%. Acute Grade 3 dermatitis and dysphagia were seen in 12% and 10%, respectively. Late toxicity, in

SUBMITTER: Laskar SG 

PROVIDER: S-EPMC12617508 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature