¹⁸F-FDG PET/CT discriminates whether rheumatoid arthritis patients are in ultrasound remission or not.

ABSTRACT:

Objectives

¹⁸F-FDG PET/CT is used for cancer evaluation but can also quantify joint inflammation in RA. We evaluated its ability to identify patients in remission as defined by US.

Methods

Sixty RA patients underwent clinical, PET/CT and US evaluations (hands and wrists). For PET/CT, the maximum standardized uptake value (SUV_max) was determined. At the patient level, the highest SUV_max, number of PET-positive joints and cumulative SUV_max were recorded. US evaluation included gray-scale and power Doppler.

Results

At the joint level, SUV_max was significantly lower when the joint was in US remission (P < 0.0001). Receiver operating characteristics curves identified a threshold of 0.86 to define joint remission

SUBMITTER: Rinkin C 

PROVIDER: S-EPMC12617742 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature