Mediterranean Diet reduces ischemic heart disease risk in diabetes patients until reversed by smoking: Evidence from UK Biobank cohort.

ABSTRACT:

Objectives

This study aims to explore the association between the Mediterranean Diet (MD) pattern and the development of ischemic heart disease (IHD) in patients with diabetes mellitus (DM) to provide a scientific basis for the management of diabetic patients.

Methods

Based on 7606 participants from the UK Biobank cohort, the adherence to the MD was assessed. The outcome indicator was the occurrence of IHD. Cox proportional hazards model was applied to estimate the Hazard ratios (HR) and 95% confidence interval (CI) of the Mediterranean Diet Score (MDS) and IHD, while trend analysis was performed using the Wald trend test. Subgroup and interaction analyses considered factors.

Results

Among 7,606 diabetic patients with a mean follow-up of 13.04 years, a total of 1,173

SUBMITTER: Fan Y 

PROVIDER: S-EPMC12617885 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature